Ce3+ doped Lu3Al5O12 (Ce:LuAG) ceramics were fabricated by the solid-state reaction method through spark plasma sintering (SPS) from 1350 °C to 1700 °C for 5 min at a pressure of 50 MPa using micro powders. The average grain size of the SPSed ceramics gradually grew from 0.42 µm (1400 °C) to 1.55 µm (1700 °C), which is nearly one order of magnitude lower than that of vacuum sintered (VSed) Ce:LuAG ceramics (~24.6 µm). Characteristic Ce3+ emission peaking at around 510 nm appeared and 92% photoluminescence intensity of room temperature can be reserved at 200 °C revealing excellent thermal stability. The maximum radioluminescence intensity reached around 3 times of VSed Ce:LuAG ceramics and 7.8 times of BGO crystals. The maximum scintillation light yield under γ-ray (137Cs) excitation reached 9634 pho/MeV

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